A B12 anemic model in immunocompromised and immunocompetent mice, demonstrates improved survival, and lower bacteria in organs, in B12 anemic animals infected with Mtb relative to non-anemic controls
Vitamin B12 Vitamin B12 (cobalamin) is an essential water-soluble vitamin required for red blood cell production, DNA synthesis, and neurologic function
Many compounds that show promise in mice fail in human trials Not FDA-approved : 5-Amino-1MQ is not approved by any regulatory agency for any indication
Vitamin B 12 (cobalamin) deficiency is a common cause of megaloblastic anemia, a variety of neuropsychiatric symptoms, and elevated serum homocysteine levels, especially in older persons
It stimulates the release of growth hormone from the pituitary gland, which can have various effects on the body, including increasing muscle mass, reducing fat mass, and improving recovery from injuries